Scientific reports of promethazine hydrochloride and codeine phosphate syrup did not involve adequate numbers of topics aged sixty five and over to ascertain whether they answer differently from more youthful subjects. Other claimed clinical knowledge has not recognized discrepancies in responses between the elderly and youthful sufferers.
To reduce the chance of dizziness and lightheadedness, rise up gradually when mounting from the sitting or lying place.
Drug interactions may adjust how your medicines operate or boost your chance for significant Uncomfortable side effects. This document isn't going to have all probable drug interactions.
Resuscitation may be essential (see OVERDOSAGE). Confined info recommend that utilization of promethazine hydrochloride during labor and shipping and delivery does not have an appreciable impact on the duration of labor or delivery and doesn't raise the chance of need for intervention while in the new child.
Animal reproduction scientific tests haven't been conducted Together with the drug combination-promethazine and codeine. It is far from recognized irrespective of whether this drug combination can result in fetal hurt when administered to the pregnant girl or can have an affect on replica potential.
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Use accurately as directed by your care group. Will not consider more than the advised dose. You could create tolerance to this medication if you take it for years.
This medication may include sugar and/or Alcoholic beverages. Caution is suggested In case you have diabetes, alcohol dependence, or liver disease. Ask your medical professional or pharmacist about making use of this merchandise safely and securely.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals less than six yrs of age, since The mix may perhaps induce deadly respiratory despair Within this age inhabitants. It is crucial that promethazine hydrochloride and codeine phosphate syrup is calculated using an correct measuring unit (see Safeguards-Information and facts for Patients).
Drug Interactions Despite the fact that sure medicines should not be employed jointly in the least, in other situations two different medicines might be employed collectively even if an interaction may well occur. In these conditions, your physician may want to change the dose, or other precautions could be important.
A Specific MedGuide are going to be provided to you personally from the pharmacist with Promethazine codeine syrup Every prescription and refill. Make sure to read this facts meticulously each time.
Promethazine hydrochloride and codeine phosphate must be specified to your Expecting woman provided that Obviously essential.
e., various copies from the gene for cytochrome P450 isoenzyme CYP2D6 or substantial morphine concentrations). These young children could be specially sensitive on the respiratory depressant consequences of codeine that's been swiftly metabolized to morphine. Codeine is contraindicated for submit-operative pain administration in these patients (see WARNINGS – Dying Associated with Extremely-Swift Metabolism of Codeine to Morphine and CONTRAINDICATIONS). The combination of promethazine hydrochloride and codeine phosphate needs to be utilised with warning in pediatric sufferers 6 decades and more mature (see WARNINGS - Use in Pediatric People).
Instruct nursing mothers to talk to the newborn’s physician right away whenever they observe these signals and, if they can't get to the health care provider right away, to go ahead and take little one to an unexpected emergency space or connect with 911 (or area unexpected emergency expert services).